Yes, I do think It can. By active, if you mean simultaneously online, then you will need to fine tune a few things(like disabling heartbeat, adding a database caching layer, and auditing for any plugin/theme
code which causes bottleneck).
If you are not using 3rd party plugin and It is base BuddyPress, I do not see any trouble. If you are using 3rd party plugins etc, you might have some bottleneck due to them. When you find that, you can either improve it or avoid it.
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